To further clarify this....
If you cannot have identical paths for Insync folders on Machine 2, then the Insync folder path on Machine 1 should not exist on Machine 2 before starting Insync.
This will cause Insync on Machine 2 to notify you that the Insync folder is missing. You can then relocate option to "find" the Insync folder (complete path to the Insync folder).
So if on the new PC it never had Google Drive or Insync before and the path does not exists, is this the correct process.
After step 4 i presume when i begin a sync it will complain about the path not being correct in why case i follow your steps to choose RELOCATE, and select the new path where my files reside correct ?
Can you screenshot or tell me exactly where this RELOCATE button or option is ?